Rat CD172 PE OX-41 100ug
货号：
552298 基本售价：
4500.0 元 规格：
-
产品信息
概述| 货号 | 552298 |
| 描述 | The OX-41 antibody reacts with the rat signal-regulatory protein (SIRP). The rat SIRP (CD172) is a 110-120-kDa type 1 transmembrane protein with three extracellular immunoglobulin superfamily domains and two intracellular ImmunoreceptorTyrosinebasedInhibitoryM otifs (ITIM). The SIRP ITIMs are phosphorylated in response to activation by growth hormone, epidermal growth factor, and integrin-mediated cell adhesion. The phosphorylated SIRP associates with tyrosine phosphatases SHP-1 and/or SHP-2. In the rat, SIRP is selectively expressed on myeloid cells (monocytes, macrophages, granulocytes, and dendritic cells) and neurons. The ligand for rat SIRP is CD47, which is similar to the interaction of the human homolog SIRP α 1 (CD172 α ) and human CD47. The SIRP/CD47 interaction is thought to be important in maintaining cellular adhesion and possibly promote T-cell activation. |
| 别名 | SIRP |
| 同种亚型 | IgG2a,κ |
| 反应种属 | Rat (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Resident peritoneal cells from cross-bred rat strains |
| 标记 | PE |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
