Hu TNF NALE MAb1 500ug
货号:
554508 基本售价:
4425.0 元 规格:
-
产品信息
概述货号 | 554508 |
描述 | The MAb1 antibody reacts with human tumor necrosis factor (TNF, aka TNF- α ) protein. TNF is a multifunctional cytokine involved in a variety of immune and inflammatory responses including hemorrhagic necrosis of tumors, septic shock, fever and autoimmune diseases. TNF can regulate the growth and differentiation of many different cell types. It is produced by different activated cell types including macrophages, T lymphocytes, NK cells, dendritic cells, endothelial cells, peripheral blood leukocytes, osteoblasts, astrocytes, mast cells, Kupffer cells, smooth muscle cells, fibroblasts and certain tumor cells. TNF exists in two biologically active forms, i.e., transmembrane and soluble forms. Upon activation, cells express transmembrane TNF glycoproteins that associate as homotrimeric complexes. After enzymatic cleavage, the extracellular region of membrane TNF sheds as a soluble homotrimer. The biologically active form of TNF has been reported to be a trimer. |
同种亚型 | IgG1 |
反应种属 | Human (QC Testing) |
来源宿主 | Mouse |
使用方法 | Neu |
性能供应商 | BD Pharmingen |
免疫原 | Human TNF Recombinant Protein |
标记 | NA/LE |
存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.This preparation contains no preservatives, thus it should be handled under aseptic conditions.
|
存储溶液 | No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2µm sterile filtered. Endotoxin level is ≤0.01 EU/µg (≤0.001 ng/µg) of protein as determined by the LAL assay. |
浓度 | 1.0 mg/ml |