Ms CD28 NALE 37.51 500ug
货号：
553294 基本售价：
4400.0 元 规格：
-
产品信息
概述| 货号 | 553294 |
| 描述 | The 37.51 antibody reacts with CD28, which is expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T cells, and at even lower density on NK cells. The expression of CD28, in splenocytes and thymocytes,has been reported to increase after activation. CD28 transcripts are found in mast cells, and cell-surface expression of CD28 is induced upon maturation or activation of mast cells. It has been reported that CD28 is not expressed on some populations of intraepithelial T lymphocytes. CD28 is a costimulatory receptor; its ligands include CD80 (B7-1) and CD86 (B7-2). The 37.51 mAb augments proliferation and cytokine production by activated T and NK cells and can provide a costimulatory signal for CTL induction. There is considerable evidence that CD28 is a costimulatory receptor involved in many, but not all, T cell-dependent immune responses. |
| 别名 | Cd28; CD28 antigen; T-cell-specific surface glycoprotein CD28 |
| 同种亚型 | IgG2,λ1 |
| 反应种属 | Mouse (QC Testing) |
| 来源宿主 | Syr hamster |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse EL-4 (T-cell lymphoma) Cells |
| 标记 | NA/LE |
| 存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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| 存储溶液 | No azide/low endotoxin: Aqueous buffered solution containing protein stabilizer, no preservative, 0.2µm sterile filtered. Endotoxin level is ≤0.01 EU/µg (≤0.001 ng/µg) of protein as determined by the LAL assay. |
| 浓度 | 1.0 mg/ml |
