Cellugyrin Pure 24/Cellugyrin 50ug
货号：
611128 基本售价：
4305.0 元 规格：
-
产品信息
概述| 货号 | 611128 |
| 描述 | Neurotransmitter release is mediated by the synaptic vesicle cycle at the presynaptic nerve terminal. This exocytic process involves vesicle docking at the plasma membrane, which is followed by priming and fusion. Following exocytosis, the empty vesicles are recycled for continued neurotransmitter release. Vesicle fusion is mediated by a protein complex consisting of both synaptic vesicle and synaptic plasma membrane components, such as synaptotagmin, synaptobrevin, and synaptogyrin. It is thought that synaptic vesicle-mediated exocytosis is very similar to other exocytic pathways. In line with this idea, cellugyrin is a synaptogyrin-like protein that is widely expressed in non-neuronal tissues. Cellugyrin and synaptogyrin share 47% amino acid sequence identity. Additionally, both cellugyrin and synaptogyrin are phosphorylated in their cytoplasmic tails by pp60c-src. This suggests a role for phosphorylation in the regulation of membrane trafficking. Thus, cellugyrin is a ubiquitously expressed exocytic protein of which synaptogyrin is a specialized neuronal version. However, the exact function of either protein in exocytosis remains to be determined. |
| 同种亚型 | IgG1 |
| 反应种属 | Rat (QC Testing) Mouse (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IF |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Rat Cellugyrin aa. 95-204 |
| 存放说明 | Store undiluted at -20°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
