Arginase I Pure 19/Arginase I 50ug
货号:
610708 基本售价:
4140.0 元 规格:
-
产品信息
概述货号 | 610708 |
描述 | Arginase converts arginine into urea plus ornithine, the final step in urea synthesis. Two different isoforms (I&II) have been isolated with approximately 60% homology at the nucleotide level. While type II is present in many tissues, Arginase I is expressed exclusively in liver. In cultured macrophages, as well as invivo, Arginase I is induced with nitric oxide synthase (NOS) and the arginase I transactivator C/EBPβ in response to lipopolysaccharide. This response occurs in a dose and time-dependent manner. While the mRNA for NOS appears as early as 2h after treatment, mRNA levels for arginase I peak after twelve hours of lipopolysaccharide treatment. Since the synthesis of nitric oxide by NOS requires arginine, the delayed induction of arginase I may be necessary for the regulation of NOS activity. |
同种亚型 | IgG1 |
反应种属 | Mouse (QC Testing) Rat, Fly (Tested in Development) |
来源宿主 | Mouse |
使用方法 | WB, IHC, IF |
性能供应商 | BD Pharmingen |
免疫原 | Human Arginase I aa. 53-207 |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
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存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
浓度 | 250 µg/ml |