14-3-3 Pure 12 50ug
货号:
561465 基本售价:
3895.0 元 规格:
-
产品信息
概述货号 | 561465 |
描述 | The family of 14-3-3 proteins has been implicated in numerous cellular processes such as neurotransmission, phospholipase activity, and calcium signaling. The 14-3-3 protein can associate with several proteins involved in cell proliferation, such as Raf-1, Bcr-Abl, middle T antigen, and CDC25 phosphatase. It appears that 14-3-3 proteins enhance the kinase activity of the Raf proto-oncogene equally as well as Ras, thus, implicating 14-3-3 proteins in the Raf/Ras/Map kinase signaling pathway. However, in spite of 14-3-3 direct association with the CDC25 phosphatase, this interaction does not increase the phosphatase activity. It has been reported that this antibody detects 14-3-3 subunits β,γ,η,θ, and ζ , but not εnorσ. |
同种亚型 | Mouse IgM |
反应种属 | Human (QC Testing) Mouse, Rat, Dog, Chicken, Frog (Tested in Development) |
性能供应商 | BD Pharmingen |
免疫原 | Human 14-3-3 |
存放说明 | Store undiluted at -20°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
浓度 | 250 µg/ml |