BAF60a Pure 23/BAF60a 50ug
货号：
611728 基本售价：
3726.0 元 规格：
-
产品信息
概述| 货号 | 611728 |
| 描述 | SWI/SNF complexes facilitate gene activation and transcription factor binding byaltering repressive chromatin structures. In mammals, SWI/SNF complexes are present inmutliple forms that include 9-12 proteins called BRG1-associatedf actors (BAFs), whichrange in molecular weight from 47 to 250 kDa. BAF60 is the homologue of the yeastSWP70 subunit of the yeast SWI/SNF complex that regulates glucocorticoidtranscription. Three isoforms of BAF60 are BAF60a, BAF60b, and BAF60c. BAF60a isubiquitously expressed and is present in the 200-kDa BRG1 complex. BAF60b andBAF60c are expressed preferentially in muscle and pancreas and may be subunits of adistinct complex that shares some subunits with BRG1 complex. In hematopoietic cells,a SWI/SNF related-complex (PYR) contains BAF57, INI1, BAF60a, and BAF170. This complex binds a 250 bp pyrimidine-rich element between the fetal and adult ß-globingenes and may facilitate human fetal-to-adult globin gene switching. Thus, BAF60proteins are components of multiple SWI/SNF complexes that regulate the transcriptionof various genes. |
| 同种亚型 | Mouse IgG2a |
| 反应种属 | Human (QC Testing) Mouse, Rat, Dog, Chicken (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse BAF60a, aa 1-91 |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
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| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
