B56 Alp Pure 23/B56 Alp 50ug
货号:
610615 基本售价:
3726.0 元 规格:
-
产品信息
概述货号 | 610615 |
描述 | Reversible phosphorylation by protein kinases and phosphatases regulates key signaling pathways in eukaryotic cells. Type 2A protein phosphatases (PP2A) are composed of two regulatory and one catalytic subunit. The active PP2A is a heterotrimer, composed of A, B, and C subunits, each encoded by different genes. B56 is a new gene family that encodes α,β, and γ proteins for the B subunit. The three B56 isoforms are approximately 70% homologous to each other and more divergent within the first 251amino acids. While the α subunit is widely expressed, the γ isoform is most abundant in heart and muscle, and the β subunit is found predominantly in brain tissue. Availability of different B subunits appears to be a key determinant in the protein substrate specificity for PP2A and could influence the subcellular distribution of the holoenzyme. |
同种亚型 | Mouse IgG1 |
反应种属 | Rat (QC Testing) Human, Mouse, Dog, Chicken, Frog (Tested in Development) |
性能供应商 | BD Pharmingen |
免疫原 | Human B56α aa. 1-162 |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
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存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
浓度 | 250 µg/ml |