Bta-Arrestin1 Pure10/Bta-Arrestin1 50ug
货号:
610550 基本售价:
3726.0 元 规格:
-
产品信息
概述货号 | 610550 |
描述 | β -Arrestins were discovered due to their ability to modulate interactions between the phosphorylated β 2-Adrenergic receptors and G proteins. This modulation results in diminished β 2-Adrenergic receptor function, also known as desensitization. Because arrestins are found at the synaptic terminals, they may provide a termination mechanism that allows the neurons to regain their original polarization and respond to a new neurotransmitter stimulus. The C-terminal region of arrestins is involved in selecting the phosphorylated and activated adrenergic receptors. The β -Arrestin1 gene encodes a protein of 418 amino acids with an approximate molecular weight of 55kDa. β -Arrestin1 protein is highly homologous to the 45kDa β -Arrestin2. Both proteins are widely expressed, but are especially abundant in the central nervous system. |
同种亚型 | Mouse IgG1 |
反应种属 | Mouse (QC Testing) Human, Rat (Tested in Development) |
性能供应商 | BD Pharmingen |
免疫原 | Rat β-Arrestin1 aa. 262-409 |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
|
存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
浓度 | 250 µg/ml |