Adaptin Gma Pure 88/Adaptin Gma 50ug
货号：
610385 基本售价：
3726.0 元 规格：
-
产品信息
概述| 货号 | 610385 |
| 描述 | Sorting of integral membrane proteins at various stages of the endocytic and secretory pathways is mediated by vesicular trafficking between a variety of organelles. Two sorting signals are tyrosine-based and dileucine-based signals that interact with heterotetrameric adaptor protein complexes (AP-1, AP-2, AP-3, and AP-4), which are associated with the vesicle coats. These coatomers contain two large Adaptin proteins (γ,α,δ, or εandβ1,β2,β3, or β4, respectively) that are noncovalently linked to one medium chain (µ1, µ2, µ3, or µ4) and one small chain ( σ1,σ2,σ3, or σ4). The AP-1 and AP-3 complexes are involved in protein sorting from the TGN and endosomes, while AP-2 adaptor complexes are involved in clathrin-mediated endocytosis. Adaptin γ shows more homology with Adaptin α than with Adaptin β. The conserved regions between Adaptins γandα could be important for binding to other components of the AP-1 and AP-2 complexes, respectively. |
| 同种亚型 | Mouse IgG1 |
| 反应种属 | Rat (QC Testing) Human, Dog, Mouse (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse Adaptin γ aa. 642-821 |
| 存放说明 | Store undiluted at -20°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
