Adaptin Bta Pure 74/Adaptin Bta 50ug
货号：
610381 基本售价：
3726.0 元 规格：
-
产品信息
概述| 货号 | 610381 |
| 描述 | Sorting of integral membrane proteins at various stages of the endocytic and secretory pathways is mediated by vesicular trafficking between a variety of organelles. Two sorting signals are tyrosine-based and dileucine-based signals that interact with heterotetrameric adaptor protein complexes (AP-1, AP-2, AP-3, and AP-4), which are associated with the vesicle coats. These coatomers contain two large Adaptin proteins ( γ,α,δ , or εandβ1,β2,β 3, or β 4, respectively) that are noncovalently linked to one medium chain (µ1, µ2, µ3, or µ4) and one small chain ( σ1,σ2,σ 3, or σ 4). The AP-1 and AP-3 complexes are involved in protein sorting from the TGN and endosomes, while AP-2 adaptor complexes are involved in clathrin-mediated endocytosis. β Adaptin subunits ( β1,β2,β3,β 4) lack sequence homology to adaptins α,γ,δ , and ε , but all of these subunits share a similar domain structure. Adaptin β 1 (also known as Adaptin β ) and β 2 (also known as Adaptin β ) have 83% amino acid identity and are found in the AP1 and AP2 complexes, respectively. |
| 同种亚型 | IgG1 |
| 反应种属 | Human (QC Testing) Mouse, Rat, Dog, Chicken, Frog (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IHC, IP, IF |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human Adaptin β aa. 75-245 |
| 存放说明 | Store undiluted at -20°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
