CD95/Fas/APO-1 Pure 13/Fas 50ug
货号:
610197 基本售价:
3726.0 元 规格:
-
产品信息
概述货号 | 610197 |
描述 | CD95 is a member of a family of cell surface receptors that includes tumor necrosis factor receptor (TNF-R), nerve growth factor receptor (NGF-R), CD40, CD27, CD30, and 4-1BB. Both murine and human Fas genes have been cloned and reportedly share 60% similarity in their amino acid sequences. CD95 (Fas) is a cell surface apoptosis-signaling molecule that is widely expressed in sites such as thymus, liver, heart, and ovary. Abnormalities in the Fas gene correlate with autoimmune features in mice and with unusually high levels of lymphocyte apoptosis in HIV-infected humans. Genetic studies have localized the Fas gene near the lpr (lymphoproliferation disease) locus on mouse chromosome 19 and further characterization reportedly has revealed that lpr is a mutation affecting the function of the Fas gene. |
别名 | Fas, APO-1 |
同种亚型 | IgG1 |
反应种属 | Human (QC Testing) Mouse, Rat, Dog, Chicken (Tested in Development) |
来源宿主 | Mouse |
使用方法 | WB, IHC(F)* |
性能供应商 | BD Pharmingen |
免疫原 | Human Fas aa. 1-163 |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
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存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
浓度 | 250 µg/ml |