Arc Pure 40/Arc 50ug
货号：
612602 基本售价：
3564.0 元 规格：
-
产品信息
概述| 货号 | 612602 |
| 描述 | Immediate early genes (IEGs) are the first to be transcribed upon cellular stimulation. Two groups of these genes have been characterized: those which encode transcription factors that indirectly influence cellular activity, and those which encode effector proteins that directly affect cellular activity. Arc (Activity-Regulated Cytoskeleton-associated protein) encodes an effector protein associated with the actin cytoskeletal matrix. In activated neurons of the hippocampus, Arc gene expression is rapidly induced. Arc protein is concentrated in the actin cortex, adjacent to the plasma membrane of the cell body and dendrites. Arc has a putative role in the maintenance of neuronal plasticity and in activity-dependent changes in dendrite function. Cocaine and D2 receptor antagonists are known to trigger the production and localization of Arc to dendrites and neuronal cell bodies. |
| 别名 | Activity-Regulated Cytoskeleton-associated protein |
| 同种亚型 | IgG1 |
| 反应种属 | Rat (QC Testing) Human, Mouse (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Rat Arc aa. 264-385 |
| 存放说明 | Store undiluted at -20°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
