ATP Synthase Alp Pure 51 50ug
货号:
612516 基本售价:
3564.0 元 规格:
-
产品信息
概述货号 | 612516 |
描述 | ATP synthase is a large enzyme complex that uses an electrochemical H+ or Na+ gradient to synthesize ATP from ADP and Pi, providing the organism with theATP needed for energy. The complex consists of two major units, F0 and F1. F0 is embedded in the inner membrane of the mitochondria and, due to its hydrophobic nature, translocates protons across this membrane. F1 is the catalytic portion in the matrix region of the mitochondria and is comprised of α,β,γ,δ, and ε subunits at a 3:3:1:1:1 ratio. The α subunit is a ubiquitous protein that is highly conserved among species. It has an adenine specific binding site that binds both ATP and ADP. There are two glycine rich regions in the sequence, the A domain and B domain, that are thought to be part of the nucleotide binding domain. It has been demonstrated that the N-terminus of the α subunit is necessary for the correct functional and structural connection of F0 to F1. Thus, the α subunit is an essential component of the ATP synthase complex and plays a role in properly orienting the F0 and F1 units. |
同种亚型 | IgG2a |
反应种属 | Human (QC Testing) Mouse, Rat, Dog, Chicken (Tested in Development) |
来源宿主 | Mouse |
使用方法 | WB, IF |
性能供应商 | BD Pharmingen |
免疫原 | Human ATP Synthase α aa. 113-220 |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
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存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
浓度 | 250 µg/ml |