PepTivator PRAME, human - RG
货号：
130-097-286 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-097-286 |
| 描述 | PepTivator® PRAME is a pool of lyophilized peptides, consisting mainly of 15-mer sequences with 11 amino acids overlap, covering the complete sequence of the preferentially expressed antigen of melanoma (PRAME) (UniProt ID: P78395).In vitro stimulation of antigen-specific T cells with PepTivator Peptide Pools causes the secretion of effector cytokines and the up-regulation of activation markers, which then allow the detection and isolation of antigen-specific T cells. |
性能| 供应商 | Miltenyi |
| 背景 | PRAME functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through certain retinoic acid receptors. Moreover, it is a melanoma antigen aberrantly expressed in chronic lymphocytic leukemia and mantle cell lymphoma. |
