PepTivator CHI3L2, human - RG
货号:
130-097-276 基本售价:
询价 规格:
EA
产品信息
概述货号 | 130-097-276 |
描述 | PepTivator® CHI3L2 is a pool of lyophilized peptides, consisting mainly of 15-mer sequences with 11 amino acids overlap, covering the complete sequence of human cartilage chitinase 3-like protein 2 (CHI3L2, YKL-39) (UniProt ID: Q15782).In vitro stimulation of antigen-specific T cells with PepTivator Peptide Pools causes the secretion of effector cytokines and the up-regulation of activation markers, which then allow the detection and isolation of antigen-specific T cells. |
性能供应商 | Miltenyi |
背景 | Cartilage chitinase 3-like protein 2 (CHI3L2, YKL-39) is secreted by articular chondrocytes, synoviocytes, lung, and heart. Increased CHI3L2 levels were found in the synovial fluids of patients with rheumatoid arthritis or osteoarthritis; autoimmunity against CHI3L2 has been discussed in this context. Elevated expression of CHI3L2 was found in some tumors, e.g., glioblastomas. |