Alp Synuclein(pY125) Pure I57-628 100ug
货号：
558246 基本售价：
7040.0 元 规格：
100ug
产品信息
概述| 货号 | 558246 |
| 描述 | The 140-amino-acid α -Synuclein protein is identical to the non-amyloid- β component precursor (NACP), a presynaptic protein involved in amyloidogenesis in Alzheimers disease (AD). This protein is expressed in brain, primarily in presynaptic nerve terminals. Although the exact function of the Synucleins has not been determined, they have been linked to the prominent neurodegenerative disorders AD and Parkinsons disease. The Tyrosine 125 (Y125) residue of α -Synuclein plays an important role in stress-induced dimerization of the protein and is phosphorylated by Pyk/RAFTK via the Src-family kinases Fyn and c-Src. The I57-628 antibody recognizes α -Synuclein phosphorylated at Y125. |
| 同种亚型 | IgG2b,κ |
| 反应种属 | Human (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | WB |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Phosphorylated peptide corresponding to the region including the Tyrosine 125 residue of α-Synuclein |
| 存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
