BLNK (pY84) PE J117-1278 50Tst
货号：
558442 基本售价：
3675.0 元 规格：
50Tst
产品信息
概述| 货号 | 558442 |
| 描述 | B cell activation is initiated by crosslinking the B cell receptor, which leads to activation of non-receptor protein tyrosine kinases (PTK), including Btk, Syk, and three Src kinases, Fyn, Lyn, and Blk. Activated PTKs then phosphorylate multiple cellular proteins involved in B lymphocyte signaling. Syk is responsible for the tyrosine phosphorylation of Bcelllink er protein (BLNK), a member of the SLP-76 family of adapter proteins. Phosphorylation of human BLNK at tyrosines 84, 178, and 189 (Y84, Y178, and Y189) creates docking sites for PLC g 2, leading to the activation of downstream signaling pathways. The J117-1278 monoclonal antibody recognizes the phosphorylated Y84 of BLNK. |
| 同种亚型 | IgG2b,κ |
| 反应种属 | Human (QC Testing) Mouse (Reactivity Confirmed in Development) |
| 来源宿主 | Mouse |
| 使用方法 | IC/FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Phosphorylated Human BLNK Peptide |
| 标记 | PE |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
|
| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
