| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Melanoma Cells Can Adopt the Phenotype of Stromal Fibroblasts and Macrophages by Spontaneous Cell Fusion in Vitro
Authors: Lajos V Kemény
Int J Mol Sci, 2016;17(6):.
Species: Human
Sample Type: Whole Cells
Pharmacological Inhibition of Protein Kinase G1 Enhances Bone Formation by Human Skeletal Stem Cells Through Activation of RhoA-Akt Signaling.
Authors: Jafari A, Siersbaek M, Chen L, Qanie D, Zaher W, Abdallah B, Kassem M
Stem Cells, 2015;33(7):2219-31.
Species: Human
Sample Type: Whole Cells
Glucocorticoids maintain human osteoclasts in the active mode of their resorption cycle.
Authors: Soe K, Delaisse JM
J. Bone Miner. Res., 2010;25(10):2184-92.
Species: Human
Sample Type: Whole Cells
Reduced ex vivo interleukin-6 production by dietary fish oil is not modified by linoleic acid intake in healthy men.
Authors: Damsgaard CT, Lauritzen L, Calder PC, Kjaer TR, Frokiaer H
J. Nutr., 2009;139(7):1410-4.
Species: Human
Sample Type: Whole Cells
Pulse treatment with the proteasome inhibitor bortezomib inhibits osteoclast resorptive activity in clinically relevant conditions.
Authors: Boissy P, Andersen TL, Lund T, Kupisiewicz K, Plesner T, Delaisse JM
Leuk. Res., 2008;32(11):1661-8.
Species: Human
Sample Type: Whole Cells
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| 背景 | CD14 is an acute phase glycoprotein that binds lipopolysaccharide endotoxins (LPS) from Gram-negative bacteria. It is primarily expressed on monocytes, macrophages, and neutrophils, and soluble forms can be secreted or shed from the cell surface. CD14 accepts LPS from its initial binding by LBP, and it can further transfer LPS to the TLR4/MD2 complex. LPS acctivation of TLR4 triggers inflammatory activation. CD14 also contributes to the response to TLR3 ligands, phosphoinositides, as well as the surfactant proteins SP-A and SP-D. |
