Blood DC Enumeration Kit, human-50 tests
货号：
130-091-086 基本售价：
询价 规格：
50Tests
产品信息
概述| 货号 | 130-091-086 |
| 描述 | The Blood Dendritic Cell Enumeration Kit was developed for easy identification and enumeration of dendritic cells (DCs) and DC subsets in whole blood or PBMCs by flow cytometry. All reagents required for the analysis are included in the kit.Applications of the kit include monitoring of peripheral blood DC frequency and number, for example, after hematopoietic stem cell mobilization3, or in the course of pathogenic infections, for example by HIV.4 Furthermore, DC numbers were determined in patients with chronic graft versus host disease5, inflammatory bowel disease6, psoriatic arthritis and rheumatoid arthritis10, under long-term immunosuppression8, lymphoproliferative disease of granular lymphocytes9, or in patients with hepatocellular carcinoma, in order to analyze the immunosuppressive role of IL-10 on circulating dendritic cells7. |
性能| 供应商 | Miltenyi |
| 背景 | The kit is based on the dendritic cell-specific surface antigens CD303 (BDCA-2), CD141 (BDCA-3), and CD1c (BDCA-1).1 The markers allow easy identification of three distinct dendritic cell subsets in blood: plasmacytoid dendritic cells (PDCs) are identified by CD303 (BDCA-2), type-1 myeloid dendritic cells (MDC1s) are identified by CD1c (BDCA-1), and type-2 myeloid dendritic cells (MDC2s) are identified by CD141 (BDCA-3) expression. The distinct dendritic cell subsets are analyzed within one sample by three-color (PDCs and MDC1s) or four-color (PDCs, MDC1s and MDC2s) flow cytometry. |
