Anti-PTK7 (CCK-4) MicroBead Kit, human
货号：
130-091-367 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-091-367 |
| 描述 | The Anti-PTK7 (CCK-4) MicroBead Kit has been developed for the isolation of PTK7+ cells from human PBMCs and bone marrow mononuclear cells (BM-MNCs). |
性能| 供应商 | Miltenyi |
| 背景 | The monoclonal anti-PTK7 antibody 188B recognizes human protein tyrosin kinase-7 (PTK7). PTK7, which is also known as colon carcinoma kinase-4 (CCK-4), is a receptor protein tyrosin kinase (RPTK)-like molecule which contains a catalytically inactive tyrosin kinase domain.1,2 PTK7 mRNA is detected in normal human melanocytes, colon carcinoma cells, as well as lung, liver, pancreas, kidney, and placenta tissue. Recently, using the specific monoclonal antibody 188B, PTK7 was shown to be expressed in blood and bone marrow, on CD303 (BDCA-2)+ plasmacytoid dendritic cells, CD141 (BDCA-3)high type-2 myeloid dendritic cells, and CD34+ hematopoietic progenitor cells (HPCs). PTK7 was detected on early (CD34+CD133+) and late (CD34+CD133-) HPCs. In tonsils, PTK7 was also found on some T cells. |
