CD62L MicroBeads, human
货号：
130-091-758 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-091-758 |
| 描述 | CD62L MicroBeads were developed for the positive selection or depletion of human CD62L+ cells from PBMCs, body fluids (e.g. bronchial lavage), or single-cell suspensions from tissue (e.g. lymphoid or tumor tissue). |
性能| 供应商 | Miltenyi |
| 背景 | The CD62L antigen is a 74 kDa glycoprotein and is a member of the selectin family of cell surface molecules, also referred to as L-selectin, LECAM-1, or LAM-1. CD62L binds a series of glycoproteins including CD34, GlyCAM-1, and MAdCAM-1. CD62L is important for homing of naive lymphocytes via the high endothelial venules to peripheral lymph nodes and Peyers patches. The CD62L antigen also contributes to the recruitment of leukocytes from the blood to areas of inflammation. Most hematopoietic cells, including most peripheral blood B cells, T cells, monocytes, dendritic cells, granulocytes, and some myeloid cells from bone marrow and thymocytes, express CD62L. CD62L is continuously endoproteolytically cleaved from the cell surface of CD62L-expressing neutrophils and lymphocytes (shedding). Proteolysis is accelerated, e.g., after antigen activation of T cells. |
