Annexin V Micro Bead Kit
货号:
130-090-201 基本售价:
询价 规格:
EA
产品信息
概述货号 | 130-090-201 |
描述 | The Annexin V MicroBead Kit was developed for positive selection or depletion of cells based on their ability to bind Annexin V. The Annexin V MicroBead Kit includes Annexin V MicroBeads and Annexin V Binding Buffer. |
性能供应商 | Miltenyi |
背景 | In most normal, viable eukaryotic cells the negatively charged phospholipid phosphatidylserine (PS) is located in the cytosolic leaflet of the plasma membrane lipid bilayer1. PS redistribution from the inner to the outer leaflet is an early and widespread event during apoptosis1,2. However, in necrosis, PS becomes accessible due to the disruption of membrane integrity2. Apart from necrosis and apoptosis, PS also becomes accessible in activated platelets3, in certain cell anomalies such as sickle cell anaemia4, in erythrocyte senescence5, upon degranulation of mast cells10, and in certain stages of B cell differentiation11. PS exposure also serves as a trigger for the recognition and removal of cells by macrophages6,9. |