Phospho-HS1 (Tyr397) (D12C1) XP® Rabbit mAb (PE Conjugate)
货号：
11880S 基本售价：
4460.0 元 规格：
100ul
产品信息
概述| 货号 | 11880S |
| 描述 | This Cell Signaling Technology antibody is conjugated to phycoerythrin (PE) and tested in-house for direct flow cytometry analysis in human cells. The antibody is expected to exhibit the same species cross-reactivity as the unconjugated Phospho-HS1 (Tyr397) (D12C1) XP® Rabbit mAb #8714. |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | F |
| 目标/特异性 | Phospho-HS1 (Tyr397) (D12C1) XP® Rabbit mAb (PE Conjugate) recognizes endogenous levels of HS1 protein only when phosphorylated at Tyr397. |
| 使用方法 | F(1:50) |
性能| 供应商 | CST |
| 标记 | PE |
| 背景 | HS1 (HCLS1, LckBP1, p75) is a protein kinase substrate that is expressed only in tissues and cells of hematopoietic origin (1,2). HS1 contains four cortactin repeats and a single SH3 domain (2). This intracellular protein is phosphorylated following immune receptor activation, which promotes recruitment of HS1 to the immune synapse (3-5). Phosphorylation of HS1 is required to regulate actin dynamics and provide docking sites for many other signaling molecules, such as Vav1 and PLCγ1 (6). HS1 also plays an important role in platelet activation (7). |
| 存放说明 | 4C |
参考图片Flow cytometric analysis of Ramos cells, untreated (blue) or treated with anti-IgM and hydrogen peroxide (green), using Phospho-HS1 (Tyr397) (D12C1) XP® Rabbit mAb (PE Conjugate).流式细胞术分析Ramos细胞，未处理(蓝色)或anti-IgM和过氧化氢处理(绿色)，使用抗体是 Phospho-HS1 (Tyr397) (D12C1) XP® Rabbit mAb (PE Conjugate)。 |
