Phospho-TBK1/NAK (Ser172) (D52C2) XP® Rabbit mAb (PE Conjugate)
货号：
13498S 基本售价：
4460.0 元 规格：
100ul
产品信息
概述| 货号 | 13498S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | F |
| 使用方法 | F(1:50) |
性能| 供应商 | CST |
| 标记 | PE |
| 背景 | TBK1 (TANK-binding kinase 1)/NAK (NF-κB activating kinase) is an IκB kinase (IKK)-activating kinase and can activate IKK through direct phosphorylation (1). TBK1 was identified through association with the TRAF binding protein, TANK, and found to function upstream of NIK and IKK in the activation of NF-κB (2). TBK1 induces IκB degradation and NF-κB activity through IKKβ. TBK1 may mediate IKK and NF-κB activation in response to growth factors that stimulate PKCε activity (1). TBK1 plays a pivotal role in the activation of IRF3 in the innate immune response (3). |
| 存放说明 | 4C |
参考图片Flow cytometric analysis of THP-1 cells differentiated with TPA #4174 (80 nM, overnight) followed by a day of rest then untreated (blue) or LPS-treated (1 μg/ml, 1 hr; green), using Phospho-TBK1/NAK (Ser172) (D52C2) XP® Rabbit mAb (PE Conjugate). |
