Androgen Receptor (D6F11) XP® Rabbit mAb (PE Conjugate)
货号:
8428S 基本售价:
4264.0 元 规格:
100ul
产品信息
概述货号 | 8428S |
描述 | This Cell Signaling Technology antibody is conjugated to phycoerythrin (PE) and tested in-house for direct flow cytometry analysis in human cells. The antibody is expected to exhibit the same species cross-reactivity as the unconjugated Androgen Receptor (D6F11) XP® Rabbit mAb #5153.该Cell Signaling Technology抗体与藻红蛋白(PE)结合,并直接用流式细胞术内部检测检测人体细胞。预计该抗体与非结合的Androgen Receptor (D6F11) XP® Rabbit mAb #5153一样,表现出相同的物种交叉反应。 |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | F |
使用方法 | F(1:50) |
性能供应商 | CST |
标记 | PE |
背景 | Androgen receptor (AR), a zinc finger transcription factor belonging to the nuclear receptor superfamily, is activated by phosphorylation and dimerization upon ligand binding (1). This promotes nuclear localization and binding of AR to androgen response elements in androgen target genes. AR plays a crucial role in several stages of male development and the progression of prostate cancer (2,3).雄激素受体(AR)是锌指转录因子,属于核受体超家族,通过磷酸化和配体结合的二聚化被激活(1)。这促进了细胞核定位和雄激素靶基因中雄激素与应答元件的结合。 AR在男性发育和前列腺癌发展的几个阶段起着至关重要的作用(2,3)。 |
存放说明 | 4C |
参考图片Flow cytometric analysis of Jurkat (blue) and LNCaP (green) cells using Androgen Receptor (D6F11) XP® Rabbit mAb (PE Conjugate).流式细胞方法检测Jurkat细胞 (蓝色)和LNCaP细胞 (绿色),使用的抗体为Androgen Receptor (D6F11) XP® Rabbit mAb (PE结合). |