MMP-9 (D6O3H) XP® Rabbit mAb (PE Conjugate)
货号：
27647S 基本售价：
4264.0 元 规格：
100ul
产品信息
概述| 货号 | 27647S |
| 反应种属 | Human |
| 来源宿主 | Rabbit IgG |
| 应用 | F |
| 使用方法 | F(1:50) |
性能| 供应商 | CST |
| 背景 | The matrix metalloproteinases (MMPs) are a family of proteases that target many extracellular proteins including other proteases, growth factors, cell surface receptors, and adhesion molecules (1). Among the family members, MMP-2, MMP-3, MMP-7, and MMP-9 have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis, and apoptosis (2-4). Research studies have shown that MMP activity correlates with cancer development (2). One mechanism of MMP regulation is transcriptional (5). Once synthesized, MMP exists as a latent proenzyme. Maximum MMP activity requires proteolytic cleavage to generate active MMPs by releasing the inhibitory propeptide domain from the full length protein (5). |
| 存放说明 | 4C |
参考图片Flow cytometric analysis of serum starved U-2 OS cells, untreated (blue) or treated with TPA (200 nM, 24 hr; green) using MMP-9 (D6O3H) XP® Rabbit mAb (PE Conjugate). |
