| 货号 | 14298S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | IF-IC/F |
| 使用方法 | F(1:50) IF-IC (1:200) |
| 供应商 | CST |
| 标记 | Alexa Fluor 488 |
| 背景 | The T-box gene family consists of transcription factors characterized by a related DNA-binding domain (T-box) of approximately 200 amino acids (1,2). The T-box genes exhibit diverse temporal and spatial patterns in the developing embryo. Studies have demonstrated members of this family play crucial roles during embryogenesis in a wide range of organisms by regulating cell fate decisions to establish the early body plan and to regulate later processes underlying organogenesis (3-5). Mutations in T-box genes are associated with many developmental defects (6). Recent studies also indicate potential roles in cancer by members of T-box family (7-9). |
| 存放说明 | 4C |
Flow cytometric analysis of human PBMCs using T-Bet/TBX21 (D6N8B) XP® Rabbit mAb (Alexa Fluor® 488) co-stained with anti-CD56 (NK cells) and anti-CD19 (B cells) antibodies. T-bet/TBX21 is clearly expressed on the CD56+ NK cell population (left plot) and absent on the CD19+ B cells (right plot). | |
Confocal immunofluorescent analysis of NK-92 (positive, left) and K-562 (negative, right) cells using T-bet/TBX21 XP® (D6N8B) Rabbit mAb (green) and β-Actin (8H10D10) Mouse mAb #3700 (red). |
