Zap-70 (136F12) Rabbit mAb (PE Conjugate)
货号:
93339S 基本售价:
4060.0 元 规格:
100ul
产品信息
概述货号 | 93339S |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | F |
使用方法 | F(1:50) |
性能供应商 | CST |
标记 | PE |
背景 | The Syk family protein tyrosine kinase Zap-70 is expressed in T and NK cells and plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement (1). Following TCR engagement, Zap-70 is rapidly phosphorylated on several tyrosine residues through autophosphorylation and transphosphorylation by the Src family tyrosine kinase Lck (2-6). Tyrosine phosphorylation correlates with increased Zap-70 kinase activity and downstream signaling events. Expression of Zap-70 is correlated with disease progression and survival in patients with chronic lymphocytic leukemia (7,8). |
存放说明 | 4C |
参考图片Flow cytometric analysis of Ramos cells (blue) and Jurkat cells (green) using Zap-70 (136F12) Rabbit mAb (PE Conjugate). |