EpCAM (VU1D9) Mouse mAb (PE Conjugate)
货号:
8995S 基本售价:
4060.0 元 规格:
100ul
产品信息
概述货号 | 8995S |
描述 | This Cell Signaling Technology antibody is conjugated to phycoerythrin (PE) and tested in-house for direct flow cytometry analysis in human cells. The antibody is expected to exhibit the same species cross-reactivity as the unconjugated EpCAM (VU1D9) Mouse mAb #2929. |
反应种属 | Human |
来源宿主 | Mouse |
应用 | F |
目标/特异性 | EpCAM (VU1D9) Mouse mAb (PE Conjugate) detects endogenous levels of total EpCAM protein. |
使用方法 | F(1:50) |
性能供应商 | CST |
标记 | PE |
背景 | Epithelial cell adhesion and activating molecule (EpCAM/CD326) is a transmembrane glycoprotein that mediates Ca2+-independent, homophilic adhesions on the basolateral surface of most epithelial cells. EpCAM is not expressed in adult squamous epithelium, but it is highly expressed in adeno and squamous cell carcinomas (1). One of the first tumor-associated antigens discovered, EpCAM has long been a marker of epithelial and tumor tissue. Because of its high expression in cancer, EpCAM has become a therapeutic target for human solid tumors of epithelial lineage (reviewed in 2,3). |
存放说明 | 4C |
参考图片Flow cytometric analysis of unpermeablized HT-29 cells using EpCAM (VU1D9) Mouse mAb (PE Conjugate) (green) compared to concentration-matched Mouse (G3A1) mAb IgG1 Isotype Control (PE Conjugate) #6899 (red). 与浓度匹配的Mouse (G3A1) mAb IgG1 Isotype Control (PE Conjugate) #6899 (红色)比较,使用EpCAM (VU1D9) Mouse mAb (PE Conjugate)标记,流式细胞仪分析非透化处理的HT-29细胞。 |