Syndecan 1 (D4Y7H) Rabbit mAb (PE Conjugate)
货号：
55987S 基本售价：
4060.0 元 规格：
100ul
产品信息
概述| 货号 | 55987S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | F |
| 使用方法 | F(1:50) |
性能| 供应商 | CST |
| 标记 | PE |
| 背景 | Syndecans are a family of type 1 transmembrane heparan sulphate proteoglycans comprising 4 members in mammals (SDC-1 to -4) (1) encoded by four syndecan genes. Syndecans are involved in embryonic development, tumorigenesis, and angiogenesis (2). The extracellular domain harbors attachment sites for heparan sulfate and chondroitin sulfate chains, facilitating interaction with an array of proteins including a plethora of growth factors. In addition, the hydrophobic C-terminal intracellular domain can interact with proteins containing a PDZ domain (2). These interactions place syndecans as important integrators of membrane signaling (3). Syndecans undergo proteolytic cleavage causing the release of their extracellular domain (shedding), converting the membrane-bound proteins into soluble molecular effectors (4). |
| 存放说明 | 4C |
参考图片Flow cytometric analysis of 293T cells (blue) and U266 cells (green) using Syndecan 1 (D4Y7H) Rabbit mAb (PE Conjugate). |
