| 货号 | 4503S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IP/F |
| 目标/特异性 | HS1 Antibody (Human Specific) detects endogenous levels of total HS1 protein. This antibody does not recognize mouse and rat HS1 proteins. HS1 has a calculated size of 54 kDa, but has an apparent molecular weight of 80 kDa on SDS-PAGE gels. |
| 使用方法 | WB(1:1000) IP (1:50) F (1:25) |
| 供应商 | CST |
| 背景 | HS1 (HCLS1, LckBP1, p75) is a protein kinase substrate that is expressed only in tissues and cells of hematopoietic origin (1,2). HS1 contains four cortactin repeats and a single SH3 domain (2). This intracellular protein is phosphorylated following immune receptor activation, which promotes recruitment of HS1 to the immune synapse (3-5). Phosphorylation of HS1 is required to regulate actin dynamics and provide docking sites for many other signaling molecules, such as Vav1 and PLCγ1 (6). HS1 also plays an important role in platelet activation (7). |
| 存放说明 | -20C |
| 计算分子量 | 80 |
Flow cytometric analysis of Jurkat cells using HS1 Antibody (Human Specific) (blue) compared to a nonspecific negative control antibody (red).流式细胞仪分析Jurkat 细胞，所用抗体为HS1 Antibody (Human Specific)(蓝色) 与非特异性对照抗体(红色)对比。 | |
Western blot analysis of cell extracts from various cell types using HS1 Antibody (Human Specific).Western免疫印迹。用HS1 Antibody (Human Specific)研究各种细胞的细胞提取液。 |
