| 货号 | 2805S |
| 反应种属 | Human |
| 来源宿主 | Rat IgG2a |
| 应用 | W/F |
| 目标/特异性 | SH2D1A (XLP 1D12) Rat mAb detects endogenous levels of total SH2D1A protein. |
| 使用方法 | WB(1:1000) F (1:400) |
| 供应商 | CST |
| 背景 | SH2D1A and SH2D1B are small, adaptor proteins with a single SH2-domain that play important signal transduction roles mediated by the signaling lymphocytic activation molecule (SLAM) family receptors (1). SH2D1A (also called SAP or SLAM-associated protein) is frequently mutated in patients with X-linked lymphoproliferative disease (Duncan’s disease), which is characterized by extreme susceptibility to Epstein-Barr virus; approximately 50 different SH2D1A mutations have been reported to date (2-4). The single SH2D1B gene in humans (also called EAT-2 or Ewings sarcomas/FLI1-activated transcript 2) is present as a pair of duplicated EAT-2A and EAT-2B genes with identical genomic organization in mouse and rat (5,6). |
| 存放说明 | -20C |
| 计算分子量 | 14 |
Flow cytometric analysis of Jurkat cells using SH2D1A (XLP 1D12) Rat mAb (blue) compared to a nonspecific negative control antibody (red).流式细胞仪分析Jurkat细胞，所用抗体为SH2D1A (XLP 1D12) Rat mAb(蓝色)与非特异性对照抗体(红色)对比。 | |
Western blot analysis of total cell lysates from Molt4 and Jurkat cells using SH2D1A (XLP 1D12) Rat mAb.Western免疫印迹。用SH2D1A (XLP 1D12) Rat mAb研究Molt4 和Jurkat 细胞的总细胞提取液。 |
