| 货号 | 4807S |
| 反应种属 | Human |
| 来源宿主 | Mouse |
| 应用 | W/IP/F |
| 目标/特异性 | Stat5a (4H1) Mouse mAb detects endogenous levels of total human Stat5a protein. |
| 使用方法 | WB(1:1000) IP (1:100) F (1:100) |
| 供应商 | CST |
| 背景 | Stat5 is activated in response to a wide variety of ligands including IL-2, GM-CSF, growth hormone and prolactin. Phosphorylation at Tyr694 is obligatory for Stat5 activation (1,2). This phosphorylation is mediated by Src upon erythropoietin stimulation (3). Stat5 is constitutively active in some leukemic cell types (4). Phosphorylated Stat5 is found in some endothelial cells treated with IL-3, which suggests its involvement in angiogenesis and cell motility (5). Stat5a and Stat5b are independently regulated and activated in various cell types. For instance, interferon treatment predominantly activates Stat5a in U-937 cells and Stat5b in HeLa cells (6). |
| 存放说明 | -20C |
| 计算分子量 | 90 |
Flow cytometric analysis of HeLa cells (red) and K-562 cells (blue) using Stat5a (4H1) Mouse mAb.流式细胞研究HeLa细胞 (红色) 和K-562 细胞 (蓝色)，所用抗体为Stat5a (4H1) Mouse mAb。 | |
Western blot analyis of extracts from K-562, MOLT-4 and TF-1 cells using Stat5a (4H1) Mouse mAb.Western免疫印迹。用Stat5a (4H1) Mouse mAb研究 K-562, MOLT-4 和 TF-1细胞的细胞提取液。 |
