货号 | FAB7136R-100UG |
简介 | Recombinant Monoclonal Antibody |
别名 | BT3.1; BTF5; BTN3A1; CD277 |
应用 | Flow Cytometry |
目标/特异性 | Detects human CD277/BTN3A1 in direct ELISAs. |
使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 11119 (Human) |
纯化方式 | Protein A or G purified from cell culture supernatant |
免疫原 | Chinese hamster ovary cell line CHO-derived recombinant human CD277/BTN3A1 Met1-Gly254 Accession # O00481 |
生物活性 | Human |
标记 | Alexa Fluor 647 |
背景 | Butyrophilin 3A1 (BTN3A1), also known as CD277, has high structural homology to the B7 superfamily of proteins and is expressed in various immune cells such as T and NK cells. BTN3A1 enhances TCR-induced cytokine production and cell proliferation. Early T-cell activation events such as TCR-induced cell signaling are increased upon BTN3A1 engagement. The BTN3A1 co-stimulatory pathway may be involved in the regulation of various cell-mediated immune responses. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of CD277/BTN3A1 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD277/BTN3A1 Alexa Fluor® 647‑conjugated Monoclonal Antibody (Catalog # FAB7136R, filled histogram) or isotype control antibody (Catalog # IC002R, open histogram). View our protocol for Staining Membrane-associated Proteins. |