货号 | IC1047R-100UG |
别名 | CAP20cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; CDKN1A; CDKN1melanoma differentiation associated protein 6; CIP1; CIP1WAF1CDK-interaction protein 1; cyclin-dependent kinase inhibitor 1A (p21, Cip1); MDA6; MDA-6; Melanoma differentiation-associated protein 6; p21; p21CIP1; p21Cip1/Waf1; PIC1; SDI1DNA synthesis inhibitor; wild-type p53-activated fragment 1 | 全称 | p21 Cyclin Dependent Kinase 4 Inhibitor 1A |
应用 | Intracellular Staining by Flow Cytometry |
目标/特异性 | Detects human p21/CIP1/CDKN1A in direct ELISAs and Western blots. |
使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 1026 (Human); 12575 (Mouse); 114851 (Rat) |
免疫原 | E. coli-derived recombinant human p21/CIP1/CDKN1A Ser2-Pro164 Accession # P38936 |
生物活性 | Human |
标记 | Alexa Fluor 647 |
背景 | p21CIP1, also called CIP1 (CDK-interacting protein 1) and CDKN1A, is a 21 kDa Cyclin/Cyclin-dependent kinase (Cdk) inhibitor that blocks cell cycle progression from G1 to S phase in the cell cycle. Because p21 is a transcriptional target of the p53 tumor suppressor, p21 expression increases in cells that contain stabilized p53 due to genotoxic stress exposure. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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