Human EOMES Allophycocyanin MAb (Clone 644730) (100 TESTS)【科瑞奥博】

产品中心

当前位置：首页>产品中心

Human EOMES Allophycocyanin MAb (Clone 644730) (100 TESTS)

货号： IC6166A 基本售价： 5373.6 元规格： 100 Tests

产品信息

概述
货号	IC6166A
别名	eomesodermin (Xenopus laevis) homolog; Eomesodermin; t box, brain, 2; T-box brain protein 2; T-box brain2; TBR2; TBR-2; TBR2eomesodermin homolog; T-brain-2
全称	Eomesodermin Homolog
反应种属	Human
应用	Intracellular Staining by Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects human EOMES in direct ELISAs. In direct ELISAs, no cross-reactivitywith recombinant human (rh) Brachyury, rhEOMES (aa 1-115), recombinant mouseEOMES (aa 1-126), rhTBX2, 3, 5, 6, 18, or 20 is observed.
使用方法	Intracellular Staining by Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	8320 (Human); 13813 (Mouse); 316052 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Hobit expression by a subset of human liver-resident CD56(bright) Natural Killer cells Authors: S Lunemann, G Martrus, H Goebels, T Kautz, A Langenecke, W Salzberger, M Koch, M J Bunders, B Nashan, KPJM van Gisber, M Altfeld Sci Rep, 2017;7(1):6676. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	E. coli-derived recombinant human EOMES Gly471-Pro686 Accession # O95936
生物活性	Human
标记	Allophycocyanin
背景	EOMES (Eomesodermin; Eo from Greek meaning “dawn”/early in mesoderm; also TBR2) is a 72 kDa member of the TBR1 subfamily, T-box family of transcription factors. It is expressed in NK and CD8⁺ T cells, where CTLA4 activation suppresses EOMES activation of IFN-gamma and granzyme B genes. It is also found in the embryo, where it occurs in forebrain floorplate and migrating neuroblasts at 12.5 weeks gestation. Notably, it is reported to undergo intercellular transfer in fetal Xenopus tissue destined to become mesoderm. Here, it synchronizes a multicellular commitment to a cell lineage.
运输条件	Blue Ice
存放说明	4℃
参考文献	Definitive Endoderm Markers Early Endodermal Lineage Markers Early Mesodermal Lineage Markers gamma delta T Cells ICC / IHC Images: EOMES Neural Progenitor Cell Markers Pluripotent Stem Cell Transcription Factors T Cell Cytokine Signaling Trophoblast Stem Cell Markers

参考图片

Detection of EOMES in Mesendoderm-differentiated BG01V Human Cells by Flow Cytometry. Mesendoderm-differentiated BG01V human embryonic stem cells were stained with Mouse Anti-Human EOMES APC‑conjugated Monoclonal Antibody (Catalog # IC6166A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules.