Human CCR10 Allophycocyanin MAb (Clone 314305) (100 TESTS)【科瑞奥博】

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Human CCR10 Allophycocyanin MAb (Clone 314305) (100 TESTS)

货号： FAB3478A-100 基本售价： 5373.6 元规格： 100 Tests

产品信息

概述
货号	FAB3478A-100
别名	CC chemokine receptor 10; C-C chemokine receptor type 10; C-C CKR-10; CC-CKR-10; CCR10; CCR-10; chemokine (C-C motif) receptor 10; G protein-coupled receptor 2; GPR2; GPR2G-protein coupled receptor 2
反应种属	Human
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detect human CCR10. Stains human CCR10-transfected cells but not irrelevant transfectants.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	2826 (Human); 12777 (Mouse); 363682 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. A role for CCL28-CCR3 in T-cell homing to the human upper airway mucosa. Authors: Danilova, E, Skrindo, I, Gran, E, Hales, B J, Smith, W A, Jahnsen, J, Johansen, F E, Jahnsen, F L, Baekkevold, E S Mucosal Immunol, 2015;8(1):107-14. Species: Human Sample Type: Whole Cells Application: Flow Plasmablasts as migratory IgG-producing cells in the pathogenesis of neuromyelitis optica. Authors: Chihara, Norio, Aranami, Toshimas, Oki, Shinji, Matsuoka, Takako, Nakamura, Masakazu, Kishida, Hitaru, Yokoyama, Kazumasa, Kuroiwa, Yoshiyuk, Hattori, Nobutaka, Okamoto, Tomoko, Murata, Miho, Toda, Tatsushi, Miyake, Sachiko, Yamamura, Takashi PLoS ONE, 2013;8(12):e83036. Species: Human Sample Type: whole cells Application: Flow Steady-state generation of mucosal IgA+ plasmablasts is not abrogated by B-cell depletion therapy with rituximab. Authors: Mei HE, Frolich D, Giesecke C, Loddenkemper C, Reiter K, Schmidt S, Feist E, Daridon C, Tony HP, Radbruch A, Dorner T Blood, 2010;116(24):5181-90. Species: Human Sample Type: Whole Cells Application: Flow CCL28 is increased in human Helicobacter pylori-induced gastritis and mediates recruitment of gastric immunoglobulin A-secreting cells. Authors: Hansson M, Hermansson M, Svensson H, Elfvin A, Hansson LE, Johnsson E, Sjoling A, Quiding-Jarbrink M Infect. Immun., 2008;76(7):3304-11. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Y3 rat myeloid cell line transfected with human CCR10 Gln8-Asn362 Accession # P46092
生物活性	Human
标记	APC
背景	CCR10 is a G protein-linked seven transmembrane domain protein expressed by T cells and B cell subsets that functions as a receptor for CCL27 and CCL28. CCR10 mediates lymphocyte migration to the skin and mucosa, and its expression is correlated with the metastatic behavior of melanomas.
运输条件	Blue Ice
存放说明	4℃
参考文献	CC Chemokines and Receptors Chemokine Receptors Th22 Cells

参考图片

Detection of CCR10 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD3 epsilon Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB100F) and either (A) Rat Anti-Human CCR10 APC‑conjugated Monoclonal Antibody (Catalog # FAB3478A) or (B) Rat IgG_2A Allophycocyanin Isotype Control (Catalog # IC006A). View our protocol for Staining Membrane-associated Proteins.

Detection of CCR10 in L1.2 Mouse Cell Line Transfected with Human CCR10 and eGFP by Flow Cytometry. L1.2 mouse pro-B cell line transfected with human CCR10 and eGFP was stained with either (A) Rat IgG_2A Allophycocyanin Isotype Control (Catalog # IC006A) or (B) Rat Anti-Human CCR10 APC‑conjugated Monoclonal Antibody (Catalog # FAB3478A). View our protocol for Staining Membrane-associated Proteins.