Human NKG2C Alexa Fluor 488 MAb (Clone 134591) (100 TESTS)【科瑞奥博】

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Human NKG2C Alexa Fluor 488 MAb (Clone 134591) (100 TESTS)

货号： FAB138G-100 基本售价： 5373.6 元规格： 100 Tests

产品信息

概述
货号	FAB138G-100
别名	CD159 antigen-like family member C; CD159c antigen; CD159c; killer cell lectin-like receptor subfamily C, member 2; KLRC2; MGC138244; NK cell receptor C; NKG2-C type II integral membrane protein; NKG2-C; NKG2CNKG2-C-activating NK receptor
全称	Natural Killer G2C
反应种属	Human
应用	Flow Cytometry
目标/特异性	Detects human NKG2C/CD159c heterodimer with CD94 in flow cytometry. It does not cross-react with the human NKG2A/CD94 heterodimer or with the human CD94 homodimer.
使用方法	Flow Cytometry: 5 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	3822 (Human)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. KIR2DL3 and KIR2DL1 show similar impact on licensing of human NK cells. Authors: Sim M, Stowell J, Sergeant R, Altmann D, Long E, Boyton R Eur J Immunol, 2016;46(1):185-91. Species: Human Sample Type: Whole Cells Application: Flow Regulatory Dendritic Cells Restrain NK Cell IFN-gamma Production through Mechanisms Involving NKp46, IL-10, and MHC Class I-Specific Inhibitory Receptors. Authors: Spallanzani R, Torres N, Avila D, Ziblat A, Iraolagoitia X, Rossi L, Domaica C, Fuertes M, Rabinovich G, Zwirner N J Immunol, 2015;195(5):2141-8. Species: Human Sample Type: Whole Cells Application: Flow 2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells. Authors: Dunphy S, Guinan K, Chorcora C, Jayaraman J, Traherne J, Trowsdale J, Pende D, Middleton D, Gardiner C Genes Immun, 2015;16(5):301-10. Species: Human Sample Type: Whole Cells Application: Flow Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection. Authors: Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M Eur J Immunol, 2013;43(2):480-7. Species: Human Sample Type: whole cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	BaF3 mouse pro-B cell line transfected with human NKG2C/CD159c and CD94
生物活性	Human
标记	Alexa Fluor 488
背景	NKG2C, also known as hemoglobin scavenger receptor, is a type I transmembrane protein expressed exclusively in monocytes and macrophages. It is a scavenger receptor cysteine-rich superfamily (SRCR-SF) protein that contains nine SRCR motifs in its extracellular region.
运输条件	Blue Ice
存放说明	4℃
参考文献	C-type Lectin Family Development of Antibodies Specific for NKG2 Family Members Human CD Marker Products Natural Killer T (NKT) Cells NKG2 Family Receptors

参考图片

Detection of NKG2C/CD159c in Human PBMC lymphocytes by Flow Cytometry. Human peripheral blood mononuclear cell (PBMC) lymphocytes were stained with Mouse Anti-Human NCAM‑1/CD56 PE‑conjugated Monoclonal Antibody (Catalog # FAB2408P) and either (A) Mouse Anti-Human NKG2C/CD159c Alexa Fluor® 488‑conjugated Monoclonal Antibody (Catalog # FAB138G) or (B) Mouse IgG₁ Alexa Fluor 488 Isotype Control (Catalog # IC002G). View our protocol for Staining Membrane-associated Proteins.