Human HLA-DR PerCP MAb (Clone L203) (100 TESTS)【科瑞奥博】

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Human HLA-DR PerCP MAb (Clone L203) (100 TESTS)

货号： FAB4869C-100 基本售价： 5234.8 元规格： 100 Tests

产品信息

概述
货号	FAB4869C-100
别名	FLJ51114; histocompatibility antigen HLA-DR alpha; HLA class II histocompatibility antigen, DR alpha chain; HLA-DRA; HLA-DRA1; major histocompatibility complex, class II, DR alpha; MHC cell surface glycoprotein; MHC class II antigen DRA; MHC Class II DR; MLRW
全称	Major Histocompatibility Complex Class II DR
反应种属	Human
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects human HLA‑DR.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	3122 (Human)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Down-regulation of complement receptors on the surface of host monocyte even as in vitro complement pathway blocking interferes in dengue infection. Authors: Marinho C, Azeredo E, Torrentes-Carvalho A, Marins-Dos-Santos A, Kubelka C, de Souza L, Cunha R, de-Oliveira-Pinto L PLoS ONE, 2014;9(7):e102014. Species: Human Sample Type: Whole Cells Application: Flow Vemurafenib enhances MHC induction in BRAF homozygous melanoma cells. Authors: Sapkota B, Hill C, Pollack B Oncoimmunology, 2013;2(1):e22890. Species: Human Sample Type: Whole Cells Application: Flow Ex vivo tetramer staining and cell surface phenotyping for early activation markers CD38 and HLA-DR to enumerate and characterize malaria antigen-specific CD8+ T-cells induced in human volunteers immunized with a Plasmodium falciparum adenovirus-vectored malaria vaccine expressing AMA1. Authors: Schwenk, Robert, Banania, Glenna, Epstein, Judy, Kim, Yohan, Peters, Bjoern, Belmonte, Maria, Ganeshan, Harini, Huang, Jun, Reyes, Sharina, Stryhn, Anette, Ockenhouse, Christia, Buus, Soren, Richie, Thomas L, Sedegah, Martha Malar J, 2013;12(0):376. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	RPMI 8866 human lymphoblastoid cells Accession # P01903
生物活性	Human
标记	PerCP
背景	HLA-DR is a transmembrane human major histocompatibility complex 2 (MHC II) family member and consists of a 34 kDa (alpha) subunit and one of several 28 kDa (beta) subunits. HLA-DR is expressed primarily by B cells and dendritic cells (DC), in which it binds peptides derived from internalized and processed antigenic proteins. It presents these peptides on the cell surface for recognition by the T cell receptor on CD4⁺ T cells. This interaction is central to antigen specificity in the adaptive immune response. HLA-DR alleles, polymorphisms, and aberrant expression are linked to a variety of diseases including autoimmunity and cancer.
运输条件	Blue Ice
存放说明	4℃
参考文献	B Cell Activation B Cell Markers Cancer Biomarkers Common Macrophage Markers Conventional/Classical Dendritic Cells Dendritic Cell Co-stimulatory Molecules Inflammatory/Monocyte-derived Dendritic Cells Langerhans and Dermal Dendritic Cells Myeloid-derived Suppressor Cells (MDSC) Plasmacytoid Dendritic Cells Regulatory T Cells (Tregs)

参考图片

Detection of HLA-DR in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human HLA-DR PerCP-conjugated Monoclonal Antibody (Catalog # FAB4869C, filled histogram) or isotype control antibody (Catalog # IC002C, open histogram). View our protocol for Staining Membrane-associated Proteins.