Human c-Myc PerCP MAb (Clone 9E10) (100 TESTS)【科瑞奥博】

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Human c-Myc PerCP MAb (Clone 9E10) (100 TESTS)

货号： IC3696C 基本售价： 5234.8 元规格： 100 Tests

产品信息

概述
货号	IC3696C
别名	avian myelocytomatosis viral oncogene homolog; BHLHE39; bHLHe39MRTL; Class E basic helix-loop-helix protein 39; c-Myc; myc proto-oncogene protein; Myc; Myc2; MYCC; myc-related translation/localization regulatory factor; Niard; Nird; Proto-oncogene c-Myc; Transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog (avian)
全称	v-Myc Avian Myelocytomatosis Viral Oncogene Homolog (Avian)
反应种属	Human
应用	Intracellular Staining by Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects endogenous human c-Myc and c-Myc tagged proteins in Western blots.
使用方法	Intracellular Staining by Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	4609 (Human); 17869 (Mouse); 24577 (Rat)
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	C-terminal region peptide of human c-Myc Ala408-Ala439 Accession # P01106
生物活性	Human
标记	PerCP
背景	Human c-Myc is a helix-loop-helix transcription factor which efficiently binds DNA after heterodimerization with the bHLH protein Max. It is often overexpressed and mutated in hematopoietic tumors. Mutations frequently result in truncation around amino acid (aa) 252, before the C-terminal DNA binding, HLH and leucine zipper domains. The 439 aa human c-Myc has one O-glycosylation site and has three Ser/Thr phosphorylation sites near the N-terminus. Human c-Myc shows 92% aa identity with mouse or rat c-Myc.
运输条件	Blue Ice
存放说明	4℃
参考文献	Apoptosis Transcription Factors and Regulators Basic Helix-Loop-Helix (bHLH) Transcription Factors Basic Leucine Zipper (bZIP) Transcription Factors Cancer Biomarkers Cancer Stem Cell Markers Cancer Stem Cell Transcription Factors Cell Cycle DNA Damage and Repair Embryonic and Induced Pluripotent Stem Cell Markers Epithelial Stem Cell Transcription Factors Hematopoietic Stem Cell Transcription Factors and Regulators ICC / IHC Images: c-Myc Natural Killer T (NKT) Cells Pluripotent Stem Cell Transcription Factors Transcription Factors in the Akt Pathway

参考图片

Detection of c‑Myc in Jurkat Human Cell Line by Flow Cytometry. Jurkat human acute T cell leukemia cell line was stained with Mouse Anti-Human c‑Myc PerCP‑conjugated Monoclonal Antibody (Catalog # IC3696C, filled histogram) or isotype control antibody (Catalog # IC002C, open histogram). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with methanol. View our protocol for Staining Intracellular Molecules.