Human CX3CR1 PerCP MAb (Clone 528728) (100 TESTS)【科瑞奥博】

产品中心

当前位置：首页>产品中心

Human CX3CR1 PerCP MAb (Clone 528728) (100 TESTS)

货号： FAB5204C-100 基本售价： 5234.8 元规格： 100 Tests

产品信息

概述
货号	FAB5204C-100
别名	Beta chemokine receptor-like 1; CCRL1; chemokine (C-C) receptor-like 1; chemokine (C-X3-C motif) receptor 1; chemokine (C-X3-C) receptor 1; CMKbRL1; CMK-BRL1; CMK-BRL-1; CMKDR1; CX3C chemokine receptor 1; Fractalkine receptor; G protein-coupled receptor 13; GPR13G-protein coupled receptor 13; GPRV28; V28; V28C-X3-C CKR-1
全称	CX3C Chemokine Receptor 1
反应种属	Human
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects human CX3CR1 in direct ELISAs.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	1524 (Human); 13051 (Mouse); 171056 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. CX3CL1/CX3CR1 and CCL2/CCR2 Chemokine/Chemokine Receptor Complex in Patients with AMD. Authors: Falk M, Singh A, Faber C, Nissen M, Hviid T, Sorensen T PLoS ONE, 2014;9(12):e112473. Species: Human Sample Type: whole cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	E. coli-derived recombinant human CX3CR1 Met1-Thr31, Leu91-Lys103, Thr168-Thr195, Lys257-Leu273 Accession # NP_001328
生物活性	Human
标记	PerCP
背景	CX3CR1 is a 40 kDa seven transmembrane chemokine receptor that is expressed on several T cell subsets, monocytes, macrophages, microglia, and epithelial cells. CX3CR1 binding to membrane bound or soluble CX3CR1/Fractalkine promotes inflammatory responses by inducing monocyte adhesion to endothelial cells and macrophage activation. CX3CR1 polymorphisms are associated with the development of chronic inflammatory disorders. Alternately spliced isoforms have extended N-terminal extracellular regions that increase the potency of CX3CR1 as a fusion co-receptor for HIV-1. Human CX3CR1 shares 82% amino acid sequence identity with mouse and rat CX3CR1.
运输条件	Blue Ice
存放说明	4℃
参考文献	Cancer Stem Cell Markers Chemokine Nomenclature Chemokine Receptors Chemokines and Receptors Chemokines and Receptors in Allergy and Asthma Chemokines and Receptors in Angiogenesis Conventional/Classical Dendritic Cells Glomerulonephritis: Beyond Inflammation Mini-review: Chemokines III Monocyte Markers Mouse Tissue-Resident Macrophage Markers Neutrophils Renal Markers T Cell Migration/Adhesion

参考图片

Detection of CX3CR1 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human CX3CR1 PerCP‑conjugated Monoclonal Antibody (Catalog # FAB5204C, filled histogram) or isotype control antibody (Catalog # IC002C, open histogram). View our protocol for Staining Membrane-associated Proteins.