Human FGF R3 Allophycocyanin MAb (Clone 136334) (100 TESTS)
货号：
FAB766A 基本售价：
5234.8 元 规格：
100 Tests
产品信息
概述| 货号 | FAB766A |
| 简介 | Clone 136334 was used by HLDA to establish CD designation |
| 别名 | CD333; CEK; EC 2.7.10; fibroblast growth factor receptor 3; HSFGFR3EX; JTK4; JTK4thanatophoric dwarfism |
全称 | Fibroblast Growth Factor Receptor 3 | | 反应种属 | Human |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects the IIIb and IIIc isoforms of human FGF R3 in direct ELISAs and Western blots. Does not cross-react with any isoforms of recombinant mouse (rm) FGF R3, rmFGF R2, recombinant human (rh) FGF R1, rhFGF R2, or rhFGF R4. |
| 使用方法 | Flow Cytometry: 10 µL/106cells
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| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 2261 (Human); 14184 (Mouse) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | Mouse myeloma cell line NS0- and Sf21-derived recombinant human FGF R3 alpha (IIIb) |
| 生物活性 | Human |
| 标记 | Allophycocyanin |
| 背景 | Fibroblast Growth Factor Receptor 3 (FGF R3) is a type I transmembrane tyrosine kinase receptor that binds FGF ligands along with heparin or heparin sulfate proteoglycans as co-factors. A segment of the membrane proximal Ig-like domain can be encoded by two different exons resulting in (IIIb) or (IIIc) isoforms. The IIIb or IIIc isoforms recognize FGF -1, -2, -4, -8b, -8e, -8f, -9, and -17b. FGF R3 plays a role in skeletal, brain, lung, intestine, kidney, and skin development. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Cancer Biomarkers
- FGF Family
- FGF Ligands
- FGF Regulators
- Fibroblast Growth Factor Superfamily
- Fibroblast Growth Factors and their Receptors
- Glial Lineage Markers
- Human CD Marker Products
- ICC / IHC Images: FGF R3
- Mini-review: Fibroblast Growth Factors (FGFs)
- Multiple Myeloma
- Receptor Tyrosine Kinases (RTKs)
- Receptor Tyrosine Kinases (RTKs) in the Akt Pathway
- Receptors in the Jak/STAT Pathway
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参考图片Detection of FGF R3 in K562 Human Cell Line by Flow Cytometry. K562 human chronic myelogenous leukemia cell line was stained with Mouse Anti-Human FGF R3 APC-conjugated Monoclonal Antibody (Catalog # FAB766A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins. |
