货号 | IC13551T-100UG |
别名 | Antigen NY-CO-13; BCC7; FLJ92943; LFS1; LFS1TRP53; p53 tumor suppressor; p53; P53cellular tumor antigen p53; Phosphoprotein p53; TP53; transformation-related protein 53; TRP53; tumor protein p53; Tumor suppressor p53 |
应用 | Intracellular Staining by Flow Cytometry |
目标/特异性 | Detects human p53. |
使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 7157 (Human); 22059 (Mouse); 24842 (Rat) |
免疫原 | E. coli-derived recombinant human p53 Asp7-Asp393 Accession # P04637 |
生物活性 | Human |
标记 | Alexa Fluor 594 |
背景 | The p53 tumor suppressor protein is a multi-functional transcription factor that regulates cellular decisions regarding proliferation, cell cycle checkpoints, and apoptosis. The importance of p53 is underscored by its mutation in over 50% of human cancers. Mice that lack one or both copies of p53 also showed an increased incidence of tumors, which makes the p53 deficient mouse a model system for studying cancer generation and progression. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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