| 货号 | FAB7098U-100UG |
| 别名 | A-10 alpha chain; FLJ26655; HLA class I histocompatibility antigen, A-1 alpha chain; HLA class I histocompatibility antigen, A-28 alpha chain; HLA class I histocompatibility antigen, A-9 alpha chain; HLA Class I; HLAA; HLA-A; HLA-ABC; major histocompatibility complex, class I, A; MHC class I antigen A*1; MHC class I antigen A*11; MHC class I antigen A*80 | 全称 | Class I Human Leukocyte Antigen |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects the human major histocompatibility complex (MHC) class I, HLA-A, B, and C. Recognizes a non-polymorphic epitope shared among products of the HLA-A, B, and C loci and immunoprecipitates both the HLA molecule and beta 2-Microglobulin. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3105 (Human) |
| 免疫原 | Membranes from human tonsillar lymphocytes |
| 生物活性 | Human |
| 标记 | Alexa Fluor 350 |
| 背景 | HLA-A, B, and C are approximately 45 kDatransmembrane glycoproteins in the major histocompatibility complex 1 (MHC I) family. Theycontain three alpha domains in their extracellular regions. HLA molecules are expressedon nearly all nucleated cells in association with the 12 kDa beta 2-Microglobulin. Thiscomplex binds peptides derived from pathogenic cytosolic or extracellularproteins such as viral or microbial proteins. It presents these peptides on thecell surface for recognition by the T cell receptor on CD8+ cytotoxicT cells. The activated cytotoxic T cell then kills the presenting cell. MismatchedMHC I alleles between a host and a donor lead to transplant rejection. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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