| 货号 | FAB6899S-100UG |
| 别名 | ACKR4; CC chemokine receptor-like 1; C-C CKR-11; CCBP2CCX CKR; CC-CKR-11; CCR11; CCR11CCR10; CCRL1; CCX-CKR; chemokine (C-C motif) receptor-like 1; orphan seven-transmembrane receptor, chemokine related; PPR1; PPR1cc motif, receptor-like protein 1; VSHK1; VSHK1CKR-11 |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human CCR11 in direct ELISAs. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 51554 (Human); 252837 (Mouse); 685243 (Rat) |
| 免疫原 | NS0 mouse myeloma cell line transfected with human CCR11 Accession # Q9NPB9 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 750 |
| 背景 | CCR11, also known as CCRL1 and CCX-CKR, is a 45 kDa 7-transmembrane segment protein that is widely expressed on stromal cells. It is a silent receptor that does not induce intracellular calcium signaling, but instead serves as a chemokine scavenger receptor. CCR11 regulates dendritic cell and thymic precursor migration by mediating the clearance of the homeostatic chemokines CCL19, 21, and 25. It is upregulated on some breast cancer cells and on bronchial epithelial cells in pulmonary sarcoidosis. Human CCR11 shares 85% amino acid sequence identity with mouse and rat CCR11. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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