| 货号 | FAB4869G-100UG |
| 别名 | FLJ51114; histocompatibility antigen HLA-DR alpha; HLA class II histocompatibility antigen, DR alpha chain; HLADR; HLA-DR; HLA-DRA; HLA-DRA1; major histocompatibility complex, class II, DR alpha; MHC cell surface glycoprotein; MHC class II antigen DRA; MHC Class II DR; MLRW | 全称 | Major Histocompatibility Complex Class II DR |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human HLA‑DR. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3122 (Human) |
| 免疫原 | RPMI 8866 human lymphoblastoid cells Accession # P01903 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 488 |
| 背景 | HLA-DR is a transmembrane human major histocompatibility complex 2 (MHC II) family member and consists of a 34 kDa (alpha) subunit and one of several 28 kDa (beta) subunits. HLA-DR is expressed primarily by B cells and dendritic cells (DC), in which it binds peptides derived from internalized and processed antigenic proteins. It presents these peptides on the cell surface for recognition by the T cell receptor on CD4+ T cells. This interaction is central to antigen specificity in the adaptive immune response. HLA-DR alleles, polymorphisms, and aberrant expression are linked to a variety of diseases including autoimmunity and cancer. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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