| 货号 | FAB4614R-100UG |
| 别名 | Calcitonin R; calcitonin receptor; CalcitoninR; CALCR; CRT; CTR; CT-R; CTR1 | 全称 | Calcitonin Receptor |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human Calcitonin R. Stains human Calcitonin R transfectants but not irrelevant transfectants. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 799 (Human); 12311 (Mouse); 116506 (Rat) |
| 免疫原 | HEK293 human embryonic kidney cell line transfected with human Calcitonin R Ala25-Ala474 Accession # NP_001733 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 647 |
| 背景 | Calcitonin receptor (CALCR) is a glycosylated 70 kDa seven-transmembrane G protein-coupled receptor that mediates the hypocalcemic effects of the peptide hormone, calcitonin. CALCR activation inhibits osteoclast-mediated bone resorption and enhances renal calcium excretion. CALCR polymorphisms and mutations have been associated with several bone disorders. Alternative splicing results in the deletion of 16 aa in the first cytoplasmic loop or 23 aa in the first extracellular region. Human CALCR shares 70%‑72% aa sequence identity with mouse and rat CACLR. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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