| 货号 | FAB4285S-100UG |
| 别名 | GLP-2 receptor; GLP2R; GLP-2R; GLP-2-R; glucagon-like peptide 2 receptor | 全称 | Glucagon-like Peptide 2 Receptor |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human GLP‑2R. Stains human GLP-2R transfectants but not irrelevant transfectants. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 9340 (Human); 93896 (Mouse); 60432 (Rat) |
| 免疫原 | HEK293 human embryonic kidney cell line transfected with human GLP-2R Met1-Ile553 Accession # O95838 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 750 |
| 背景 | GLP-2R is a member of the class II glucagon-secretin G protein-coupled receptor superfamily. It is expressed on enteroendocrine cells in the gut where it mediates the positive effects of GLP2 on villus height, crypt depth and intestinal energy absorbtion. After stimulating a cAMP response, lipid raft-dependent internalization of GLP‑2R results in rapid desensitization to GLP2. Extracellular portions of human GLP-2R show approximately 80% amino acid identity with corresponding regions of mouse GLP-2R. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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