| 货号 | FAB3659G-100UG |
| 别名 | AGTR2; AGTR-2; angiotensin II receptor, type 2; Angiotensin II type-2 receptor; angiotensin receptor 2; AT2; AT2ATGR2; AT2R; MRX88; MRX88type-2 angiotensin II receptor | 全称 | Angiostensin II Type 2 Receptor |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human AGTR‑2. Stains human AGTR-2-transfected cells but not irrelevant transfectants. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 186 (Human); 11609 (Mouse); 24182 (Rat) |
| 免疫原 | HEK293 human embryonic kidney cell line transfected with human AGTR-2 Met1-Ser363 Accession # P50052 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 488 |
| 背景 | AGTR-2, also known as AT2, is a 7-transmembrane protein that belongs to family 1 of G protein-coupled receptors. Both AGTR-2 and AGTR‑1 bind Angiotensin II and function in the control of hemodynamics. In contrast to AGTR‑1, which promotes vasoconstriction and cell proliferation, AGTR-2 inhibits growth and promotes apoptosis. In addition, Angiotensin II-induced AGTR-2 signaling induces the release of nitric oxide in the heart, kidney, and brain and participates in tissue morphogenesis and repair. Human AGTR-2 shares 92% amino acid sequence identity with mouse and rat AGTR-2. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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